top of page
  • Facebook
  • LinkedIn

NISSTEX AND PROSTATE

A promising potential in supporting urinary health and managing prostate-related issues such as prostatism and urinary retention.


How Black Seed Helps with Urinary and Prostate Health


Black seed contains thymoquinone, a powerful bioactive compound with multiple therapeutic properties:


Anti-Inflammatory Effects

  • Helps reduce inflammation in the prostate, which is crucial for conditions like benign prostatic hyperplasia (BPH) and prostatitis.

  • Inflammation is a key contributor to urinary retention and discomfort in men with prostate issues.


✅Antioxidant Properties

  • Protects prostate cells from oxidative stress, potentially slowing the progression of prostate enlargement and reducing cancer risk.


✅Urinary Benefits

  • May improve bladder emptying and reduce symptoms like frequent urination, weak stream, and urgency.

  • Clinical studies have shown black seed can help with urinary incontinence, especially in older or menopausal individuals. 


ree

How NISSTEX Enhances These Benefits.

NISSTEX is a chewable tablet formulated by Prof. Dr. Mustafa Ali Mohd, to deliver the complete spectrum of black seed’s therapeutic compounds — both oil-soluble and water-soluble — through advanced extraction technology.  

It undergoes specialized processing and includes essential complementary compounds to ensure optimal activation and full functionality of Nigella sativa’ s bioactive components within the human body.



Key Features of NISSTEX:


  • Full-spectrum extraction: Unlike regular black seed oil or powder, NISSTEX captures all active compounds for maximum efficacy. To date, this is the only one of its kind in the market.

  • Synergistic formula on: Combines black seed with monk fruit and essential nutrients to enhance anti-inflammatory, antioxidant, and immune-modulating effects.

  • No side effects: Designed for safe, long-term use without digestive discomfort.


Potential Benefits for Urinary & Prostate Health:


Reduces inflammation in the urinary tract and prostate.

  • Supports bladder control and reduces nocturia (frequent night urination).

  • May help regulate hormones and reduce stress, which can indirectly improve urinary symptoms.

  • Promotes detoxification which supports kidney and liver health — both important for urinary function.


Issue

Black Seed

Nisstex

Prostatism

Anti-inflammatory, antioxidant

Enhanced delivery of thymoquinone,

multisystem support

Urinary

Retention

Improves bladder emptying,

reduces inflammation

Synergistic effects for better flow and control

Incontinence

Shown to reduce symptoms in clinical trials

Holistic support including stress and sleep regulation


Mechanisms of Black Seed (Nigella sativa)


  1. Anti-inflammatory Action

    Key Compound: Thymoquinone

Mechanism:
  • Inhibits NF-κB and IRAK1 pathways, which are central to the production of pro-inflammatory cytokines like TNF-α, IL-6, and IL-1β.

  • Reduces infiltration of immune cells into prostate tissue, lowering inflammation and swelling.

  • In rat models of bacterial prostatitis, Thymoquinone reduced oxidative markers (MDA, NO) and improved histological damage.


  1. Antioxidant Defense

Mechanism:
  • Scavenges reactive oxygen species (ROS) such as superoxide and hydroxyl radicals.

  • Enhances activity of antioxidant enzymes like glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT).

  • Protects prostate and urinary tract cells from oxidative stress-induced damage, which contributes to BPH and urinary retention.


3. Antiproliferative & Apoptotic Effects

Mechanism:
  • TQ induces apoptosis in abnormal prostate cells by modulating p53, STAT3, and PI3K/AKT pathways.

  • Prevents angiogenesis (formation of new blood vessels) that supports tumor growth.

  • Selectively targets cancerous cells while sparing normal prostate cells.


4. Diuretic and Urinary Flow Enhancement

Mechanism:
  • Black seed has mild diuretic properties, increasing urine output and helping relieve retention.

  • Modulates urinary mineral balance, reducing calcium and oxalate levels, which may help prevent stone formation and improve flow.


Mechanisms of NISSTEX (Enhanced Black Seed Formulation)


Nisstex is a chewable nutraceutical developed by Prof. Dr. Mustafa Ali Mohd, designed to deliver full-spectrum black seed benefits with enhanced bioavailability and safety.


Summary Table


Effect

Black Seed Mechanism

Nisstex Enhancement

Anti-inflammatory

Inhibits NF-κB, IRAK1,

reduces cytokines

Full-spectrum delivery + synergistic anti-inflammatory

agents

Antioxidant

Scavenges ROS, boosts GPx,

SOD, CAT

Enhanced absorption + monk fruit

antioxidants

Prostate Cell

Regulation

Induces apoptosis, inhibits

angiogenesis

Precision targeting via optimized

formulation

Urinary Flow

Diuretic, mineral modulation

Kidney support + improved flow and

detox

Safety &

Absorption

Natural but variable

Scientifically standardized, safe for all ages


 
 
 

Comments


profmus © 2025 - All Rights Reserved.

bottom of page