NISSTEX AND PROSTATE
- xhteh9
- 1 day ago
- 3 min read
A promising potential in supporting urinary health and managing prostate-related issues such as prostatism and urinary retention.
How Black Seed Helps with Urinary and Prostate Health
Black seed contains thymoquinone, a powerful bioactive compound with multiple therapeutic properties:
✅Anti-Inflammatory Effects
Helps reduce inflammation in the prostate, which is crucial for conditions like benign prostatic hyperplasia (BPH) and prostatitis.
Inflammation is a key contributor to urinary retention and discomfort in men with prostate issues.
✅Antioxidant Properties
Protects prostate cells from oxidative stress, potentially slowing the progression of prostate enlargement and reducing cancer risk.
✅Urinary Benefits
May improve bladder emptying and reduce symptoms like frequent urination, weak stream, and urgency.
Clinical studies have shown black seed can help with urinary incontinence, especially in older or menopausal individuals.

How NISSTEX Enhances These Benefits.
NISSTEX is a chewable tablet formulated by Prof. Dr. Mustafa Ali Mohd, to deliver the complete spectrum of black seed’s therapeutic compounds — both oil-soluble and water-soluble — through advanced extraction technology.
It undergoes specialized processing and includes essential complementary compounds to ensure optimal activation and full functionality of Nigella sativa’ s bioactive components within the human body.
Key Features of NISSTEX:
Full-spectrum extraction: Unlike regular black seed oil or powder, NISSTEX captures all active compounds for maximum efficacy. To date, this is the only one of its kind in the market.
Synergistic formula on: Combines black seed with monk fruit and essential nutrients to enhance anti-inflammatory, antioxidant, and immune-modulating effects.
No side effects: Designed for safe, long-term use without digestive discomfort.
Potential Benefits for Urinary & Prostate Health:
Reduces inflammation in the urinary tract and prostate.
Supports bladder control and reduces nocturia (frequent night urination).
May help regulate hormones and reduce stress, which can indirectly improve urinary symptoms.
Promotes detoxification which supports kidney and liver health — both important for urinary function.
Mechanisms of Black Seed (Nigella sativa)
Anti-inflammatory Action
Key Compound: Thymoquinone
Mechanism:
Inhibits NF-κB and IRAK1 pathways, which are central to the production of pro-inflammatory cytokines like TNF-α, IL-6, and IL-1β.
Reduces infiltration of immune cells into prostate tissue, lowering inflammation and swelling.
In rat models of bacterial prostatitis, Thymoquinone reduced oxidative markers (MDA, NO) and improved histological damage.
Antioxidant Defense
Mechanism:
Scavenges reactive oxygen species (ROS) such as superoxide and hydroxyl radicals.
Enhances activity of antioxidant enzymes like glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT).
Protects prostate and urinary tract cells from oxidative stress-induced damage, which contributes to BPH and urinary retention.
3. Antiproliferative & Apoptotic Effects
Mechanism:
TQ induces apoptosis in abnormal prostate cells by modulating p53, STAT3, and PI3K/AKT pathways.
Prevents angiogenesis (formation of new blood vessels) that supports tumor growth.
Selectively targets cancerous cells while sparing normal prostate cells.
4. Diuretic and Urinary Flow Enhancement
Mechanism:
Black seed has mild diuretic properties, increasing urine output and helping relieve retention.
Modulates urinary mineral balance, reducing calcium and oxalate levels, which may help prevent stone formation and improve flow.
Mechanisms of NISSTEX (Enhanced Black Seed Formulation)
Nisstex is a chewable nutraceutical developed by Prof. Dr. Mustafa Ali Mohd, designed to deliver full-spectrum black seed benefits with enhanced bioavailability and safety.






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